Professor Chris Clark is Professor of Imaging and Biophysics at UCL. His research focus is on the development and application of imaging for the understanding of neurological disability. The development of these methods will lead to better neurosurgical planning in both children and adults.
Treatment for children with medulloblastoma, an aggressive type of brain tumour, is frequently accompanied by damage to the brain with long-term implications such as memory loss. When grouped together these effects are called Cerebellar Mutism Syndrome (CMS) or Posterior Fossa Syndrome, because of the location of the tumour at the back of the brain.
Diffusion tensor imaging or DTI, is a type of MRI that measures the flow of water around the brain, and around the tumour, which allows us to see precisely where damage may have occurred. The technique is yet to be developed for medulloblastoma, and this will be the focus of Professor Clark's project with us.
If these vulnerable areas of the brain can be avoided during treatment it would prevent CMS and the unnecessary brain injuries that severely affect a child's quality of life.
Research is the only way we will discover kinder, more effective treatments and, ultimately, stamp out brain tumours – for good! However, brain tumours are complex and research in to them takes a great deal of time and money.
Across the UK, over 100,000 families are facing the overwhelming diagnosis of a brain tumour and it is only through the generosity of people like you can we continue to help them.
But, by setting up a regular gift – as little as £2 per month - you can ensure that families no longer face this destructive disease.