Solving the mystery behind Cerebellar Mutism Syndrome
- Official title: Nordic and UK study of the cerebellar mutism syndrome (CMS) in children with brain tumours of the posterior fossa
- Lead researcher: Mr Conor Mallucci
- Where: Alder Hey Children's Hospital
- When: June 2017 - May 2020
- Cost: £111,612 over three years
- Research type: Paediatric, Medulloblastoma (High Grade), Clinical
Mr Mallucci is a Paediatric Neurosurgeon with over 14 years of experience and is currently at the Alder Hey Children's Hospital.
He is the surgical lead for ependymoma studies and craniopharyngioma. He has over 75 publications in international peer reviewed journals and is currently deputy editor of the British Journal of Neurosurgery.
Mr Mallucci will be carrying out a multi-centre study to investigate Cerebellar Mutism Syndrome (CMS), a.k.a. Posterior Fossa Syndrome, a serious and poorly understood late effect resulting from surgical complication. It is seen in up to 25% of children after removing tumours from the very back of the skull, known as the cerebellum.
This study will explore the surgical methods associated with CMS and determine whether some patients are at higher risk of developing CMS in order to enhance treatment and improve quality of life. With a greater understanding of CMS they hope to ultimately prevent and reduce the number of children who have CMS after surgery.
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