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Side-effects of stereotactic radiotherapy

Stereotactic radiotherapy treatments generally have fewer side-effects than conventional radiotherapy, as the area being treated is generally smaller and the dose that the healthy tissue receives is smaller.

Short term side-effects

It is very common to feel tired for a few days after stereotactic radiotherapy (SRT). Make sure you let yourself rest. Some people experience feelings of nausea, dizziness or faintness directly afterwards. This is uncommon, however, as doctors often give steroids before or immediately after your treatment, to help prevent these side-effects caused by swelling of the brain

If you had a head frame, the areas where the frame was attached to your skull may be tender and may bleed slightly or be slightly itchy as they heal. Your health team will give you information about keeping these clean to reduce the risk of infection at the pin sites.

You may also have a dull headache once the anaesthetic wears off. This can be eased with painkillers.

These side effects are generally short-lived.

If your tumour was near the surface of your skull, you may lose some hair, but hair loss is rarely a side-effect of stereotactic radiotherapy treatments.

There is also a slight possibility that you may have a seizure (fit) after radiosurgery (SRS). This is more likely in people who have had seizures before the treatment. As a result, although seizures are rare, the DVLA (DVA in N. Ireland) does not allow you to drive for at least 1 month after your treatment, even if you have not had seizures previously.If you experience any side-effects, particularly ones that you are concerned about, speak to your doctor.

It is also important to be aware that radiotherapy of any type can cause swelling in the tissue around the treated area. This can make it look like the tumour is growing again on a post treatment MRI scan. This is known as 'pseudo-progression' and can make it difficult to assess the effect of the radiotherapy for a period of time after treatment.

Long term side-effects

As SRT treatments involve a very high dose of radiation, some people can develop a section of dead cells in the treated area known as 'radiation necrosis.'

This can happen from months to decades after treatment, but it generally occurs six months to two years after the SRT procedure. It is more likely if you have chemotherapy as part of your treatment.

Most people who develop radiation necrosis will have no symptoms as the area will be very small. If symptoms occur due to swelling steroids can be given to treat this. Occasionally, however, surgery may be required to remove the dead tissue.

If you have any concerns, discuss them with your health team.

If you have further questions, need to clarify any of the information on this page, or want to find out more about research and clinical trials, please contact our team:

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